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KMID : 0985520120170020061
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Korean Journal of Pancreas and Biliary Tract
2012 Volume.17 No. 2 p.61 ~ p.66
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A Case of Pancreatic Serotonin-Producing Neuroendocrine Tumor Mimicked Pancreas Cancer with Multiple Distant Metastasis
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Park Sun-Man
Koh Dong-Hee
Kim Yong-Jin
Hang Jung-Wan
Choi Min-Ho
Jang Hyun-Joo
Kae Sea-Hyub
Lee Jin
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Abstract
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Pancreatic serotonin-producing neuroendocrine tumors(NETs) are exceedingly rare tumors that originate from the enterochromaffin cells of the pancreatic neuroendocrine system. Although pancreatic serotonin-producing NETs grow slowly and show an indolent clinical behavior, they are potentially malignant. Due to the late onset of clinical symptoms and delayed diagnosis of the tumor, there was a high incidence of distant metastases and an unfavorable overall prognosis. The diagnosis of pancreatic serotonin-producing NETs should be based on the measurement of serotonin in serum or its demonstration in the tumor and/or by the measurement of 5-Hydroxyindoleacetic acid(5-HIAA) in urine. We experienced a rare case of pancreatic serotonin-producing NET mimicked pancreas cancer with multiple distant metastasis and report here with literature review.
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KEYWORD
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pancreas, neuroendocrine tumors, serotonin
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